Abstract

Ultra-low-field MRI can improve access, but acquisitions at tens of millitesla typically exhibit lower signal-to-noise ratio (SNR) and less stable tissue contrast than clinical high-field scans. A physics- conditioned latent generative method is presented for same-contrast cross-field MRI synthesis. For MRIxFields Task 2, a shared model maps 0.1T inputs to 1.5, 3, 5, and 7T under explicit acquisition-parameter conditioning. Paired slices are embedded by a variational autoencoder (VAE). A residual predictor conditioned on (B0,TR,TE,TI) estimates a coarse latent target, and a latent denoising diffusion bridge model (DDBM) refines the source-to-target transition. The model is pretrained on public paired 64mT/3T data and adapted on three paired challenge subjects. On the official Task-2 evaluation, the method ranks first on SSIM (primary metric; 0.878) and Dice (0.823). Acquisition parameters enter the mapping, while anatomy is represented in a compact latent space.

Links to Paper and Supplementary Materials

Main Paper (Open Access Version): https://papers.miccai.org/miccai-2026-sat/paper/MRIxFields2026_019.pdf

SharedIt Link: Not yet available

SpringerLink (DOI): Not yet available

Supplementary Material: https://papers.miccai.org/miccai-2026-sat/supp/MRIxFields2026_019_supp.pdf

Link to Open Review

Open Review Page: https://openreview.net/forum?id=P6C7dqAhTX

BibTex

@InProceedings{CheSai_PhysicsConditioned_MICCAISAT2026,
        author = { Cheng, Sai AND Chen, Linxin AND Zong, Fangrong},
        title = { { Physics-Conditioned Latent Diffusion Bridges for Ultra-Low-Field to Multi-Field MRI Synthesis } },
        booktitle = {Medical Image Computing and Computer Assisted Intervention -- MICCAI 2026 Workshops and Challenges},
        year = {2026},
        publisher = {Springer Nature Switzerland},
        volume = {LNCS 17274},
        month = {pending},
        page = {pending}
}


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