Abstract

Cross-field brain MRI translation changes field-dependent image appearance while preserving anatomy. We study same-contrast translation across five field strengths and three contrasts with one shared model. DINOv3-PE-DPT keeps the public DINOv3 ViT-H+/16 weights frozen and adapts them to MRI synthesis through a learned nine-channel input projection, MRI-specific conditioning, and a Dense Prediction Transformer (DPT) decoder. The complete MRI adaptation involves approximately 19.78M learned parameters, about 2.3% of the 861.2M-parameter checkpoint, while the final continuation updates only 215,304 shared low-rank DPT parameters. Under the local MRIxFields2026 protocol with 180 reassembled 30- slice central-slab outputs from 15 reporting subjects, DINOv3-PE-DPT achieves SSIM 0.9023, nRMSE 0.2342, and LPIPS 0.1339, compared with 0.7397 for the released StarGAN v2 prediction tree, 0.8365 for source copy, and 0.8418 for the paired-training affine diagnostic. His- torical branch comparisons show that DPT and LoRA variants already reach 0.895–0.902 SSIM; the final continuation changes SSIM by about 0.0003 relative to its parent and has slightly worse LPIPS. Router diagnostics show near-uniform mixtures and score-equivalent uniform routing, so the supported finding is unified dense prediction using frozen public DINOv3 weights and MRI-specific adaptation, not expert-router specialization. The study is limited to an adaptively developed local benchmark, without evidence of pathology preservation or external- cohort generalization.

Links to Paper and Supplementary Materials

Main Paper (Open Access Version): https://papers.miccai.org/miccai-2026-sat/paper/MRIxFields2026_014.pdf

SharedIt Link: Not yet available

SpringerLink (DOI): Not yet available

Supplementary Material: Not Submitted

Link to Open Review

Open Review Page: https://openreview.net/forum?id=oSyaVphupx

BibTex

@InProceedings{WuYue_DINOv3PEDPT_MICCAISAT2026,
        author = { Wu, Yuehan AND Wang, Lu AND Ge, Siyuan AND Liu, Bo AND Hwang, Jenq-Neng AND Zhu, Cheng Cheng},
        title = { { DINOv3-PE-DPT: Frozen Public DINOv3 Weights for Cross-Field Brain MRI Translation } },
        booktitle = {Medical Image Computing and Computer Assisted Intervention -- MICCAI 2026 Workshops and Challenges},
        year = {2026},
        publisher = {Springer Nature Switzerland},
        volume = {LNCS 17274},
        month = {pending},
        page = {pending}
}


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