Abstract

Deep learning architectures for medical imaging often rely on encoders pre-trained on natural images despite the domain gap with 3D brain MRI. We present an extensive benchmark of 8 natural-image-pretrained and 10 medical-image-pretrained vision encoders on age/sex prediction and disease classification (ADNI, PPMI), finding 2D natural-image encoders perform most favorably even against models pretrained on over 100k brain MRI volumes.

Links to Paper and Supplementary Materials

Main Paper (Open Access Version): https://papers.miccai.org/miccai-2026-sat/paper/MLCN_2026_038.pdf

SharedIt Link: Not yet available

SpringerLink (DOI): Not yet available

Supplementary Material: Not Submitted

Link to Open Review

Open Review Page: https://openreview.net/forum?id=DW0ULsgbK4

BibTex

@InProceedings{FalPie_Representation_MICCAISAT2026,
        author = { Falconnier, Pierre AND Trombetta, Robin AND Duchateau, Nicolas AND Lartizien, Carole},
        title = { { Representation Learning for 3D Brain Imaging: A Benchmark } },
        booktitle = {Medical Image Computing and Computer Assisted Intervention -- MICCAI 2026 Workshops and Challenges},
        year = {2026},
        publisher = {Springer Nature Switzerland},
        volume = {LNCS 17255},
        month = {pending},
        page = {pending}
}


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