Abstract

Foundation models are increasingly used as image feature extractors for mammography, but their robustness under external domain shift remains unclear. We benchmark 15 foundation-model backbones across breast density, BI-RADS severity, and cancer status using a unified frozen-backbone linear-probe protocol, training on 3 source datasets and evaluating on 12 task-compatible out-of-distribution (OOD) datasets after label harmonization. Mammography-specific vision-language models (Mammo-FM and MaMA) provide the strongest mean OOD performance, but robustness is not explained by mammography exposure alone. DINOv3 remains a competitive vision-only baseline, and mammography-adapted pretraining does not consistently improve generalization. Dataset-level analysis further shows that even leading models show heterogeneous performance across datasets. Feature-space inspection reveals that useful representations can preserve clinical signal while retaining dataset and acquisition structure. These findings highlight dataset-level OOD evaluation as a central criterion for assessing mammography representations.

Links to Paper and Supplementary Materials

Main Paper (Open Access Version): https://papers.miccai.org/miccai-2026-sat/paper/Deep_Brea3th_014.pdf

SharedIt Link: Not yet available

SpringerLink (DOI): Not yet available

Supplementary Material: Not Submitted

Link to Open Review

Open Review Page: https://openreview.net/forum?id=rFaTFPqAo3

BibTex

@InProceedings{NguGia_Benchmarking_MICCAISAT2026,
        author = { Nguyen, Giang AND Mehta, Raghav AND Stanley, Emma A. M. AND Xia, Tian AND Nguyen, Thi Hao AND Pham, Hieu AND Glocker, Ben},
        title = { { Benchmarking the Robustness of Foundation Models for Mammography under Domain Shift } },
        booktitle = {Medical Image Computing and Computer Assisted Intervention -- MICCAI 2026 Workshops and Challenges},
        year = {2026},
        publisher = {Springer Nature Switzerland},
        volume = {LNCS 17256},
        month = {pending},
        page = {pending}
}


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