Abstract

In this work, we explore MammoClaw, a training-free agent framework that leverages frozen MLLMs for mammography analysis. To support agentic investigation, we equip the agent with lightweight mammography-specific tools for targeted image analysis, including ROI, paired-view, and contralateral-breast examination. MammoClaw iteratively gathers evidence through these tools, while skill evolution enables nonparametric adaptation by transforming failed trajectories into reusable guidance for later runs. We evaluate the framework on BI-RADS assessment and breast density estimation tasks. In our experiments, we find that tools alone do not reliably improve performance, whereas evolved skills can improve tool-use behavior and performance in some settings. Beyond these results, MammoClaw enables transparent inspection of evidence acquisition, tool interactions, and failure modes, facilitating the analysis and auditing of agent behavior. We view this work as an exploratory study of training-free, self-evolving agentic approaches for mammography and hope it provides a concrete starting point for future work on mammography-specific tools and self-evolution mechanisms. We release our code at https://krishnakanthnakka.github.io/mammoclaw.

Links to Paper and Supplementary Materials

Main Paper (Open Access Version): https://papers.miccai.org/miccai-2026-sat/paper/Deep_Brea3th_010.pdf

SharedIt Link: Not yet available

SpringerLink (DOI): Not yet available

Supplementary Material: https://papers.miccai.org/miccai-2026-sat/supp/Deep_Brea3th_010_supp.pdf

Link to Open Review

Open Review Page: https://openreview.net/forum?id=yObV6xqJ2Z

BibTex

@InProceedings{NakKri_MammoClaw_MICCAISAT2026,
        author = { Nakka, Krishna Kanth},
        title = { { MammoClaw: Towards Skill-Evolving Agent Harness for Breast Cancer Mammography Analysis } },
        booktitle = {Medical Image Computing and Computer Assisted Intervention -- MICCAI 2026 Workshops and Challenges},
        year = {2026},
        publisher = {Springer Nature Switzerland},
        volume = {LNCS 17256},
        month = {pending},
        page = {pending}
}


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